Harry Balbo (Flanery), a fearful salesman of pieces for pipes, runs into a violent crime in a alley. He thinks he has seen an assassin that cuts off heads, in fact he's dealing with a vampire woman (Ayanna) who is able to decapitate a man and disappear. Nobody believes him, neither the police. Harry, obsessed by the woman, soon contacts a neighbor named Strickland (Biehn), which is a vampire-hunter, because he wants to find her. They begin to track the zone where she hunts to locate her refuge...